王东辉

王东辉

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职称: 副教授

教育背景:

2012.9-2017.7 中科院上海硅酸盐研究所 博士

2008.9-2012.6 四川大学 学士

工作履历:

2019.6-至今 河北工业大学 讲师/副教授

2017.8-2019.6 中科院上海硅酸盐研究所 助理研究员

研究领域与承担项目:

研究领域:

医用金属材料表面改性

主要从事生物医用钛、镍钛、镁合金表面改性研究,着重研究植/介入材料所涉及的关键科学问题-抗癌能力和抗菌能力:

(1)医用金属材料表面改性与修饰

(2)抗腐蚀涂层构建

(3)抗菌、抗癌、生物活性薄膜/涂层

(4)材料对细胞、细菌行为的识别与调控

基金和项目:

(1)国家自然科学基金委员会,青年项目,51901239,钛表面微环境自响应载药薄膜构建及其选择性生物学效应研究,2019-01至2022-12

(2)河北省自然科学基金,青年项目,E2021202001,镍钛表面热化疗一体化载药薄膜构建及其抗胆囊癌机制,2021-01至2023-12

(3)上海市科学技术委员会,“扬帆计划”项目18YF1426900,微环境响应层状双氢氧化物薄膜构筑和性能研究,2018-05至2021-04

(4)中科院上海硅酸盐研究所高性能陶瓷和超微结构国家重点实验室,主任青年基金项目,SKL201706,镍钛表面智能响应薄膜构筑和性能研究,2018-01至2020-12

奖励与荣誉:

(1)入选“上海科技英才扬帆计划”

(2)河北工业大学“元光学者”

(3)中国生物材料学会医用金属材料分会学术年会“优秀青年学者”

学术成果:

(1)Wang DH, Tan Ji, Zhu HQ, Mei YF, Liu XY*; Biomedical Implants with Charge-Transfer Monitoring and Regulating Abilities. Advanced Science 2021, 8 (16).

(2)Yin YJ,Jian LJ,Li BE,Liang CY,Han XL,Zhao XF,Wang DH*,Mg-Fe layered double hydroxides modified titanium enhanced the adhesion of human gingival fibroblasts through regulation of local pH level. Materials Science & Engineering C, 2021,112485.

(3)Li BE, Zhang L, Wang DH*, Peng F*, Zhao XF, Liang CY, Li HP, Wang HS. Thermosensitive-hydrogel-coated titania nanotubes with controlled drug release and immunoregulatory characteristics for orthopedic applications, Materials Science & Engineering C, 2021,122.

(4)Peng F, Cheng S, Zhang RY, Li M, Zhou JL, Wang DH*, Zhang Y*, Zn-contained mussel-inspired film on Mg alloy for inhibiting bacterial infection and promoting bone regeneration. Regenerative Biomaterials, 2020. doi: 10.1093/rb/rbaa044

(5)Wang DH, Li QW, Qiu JJ, Zhang XM, Liu XY*. Corrosion motivated ROS generation helps endow titanium with broad-spectrum antibacterial abilities. Advanced Materials Interfaces,2019, 1900514.

(6)Wang DH, Ge NJ, Yang TT, Liu CC, Peng F, Li QW, Liu XY*. NIR-triggered crystal phase transformation of NiTi-layered double hydroxides films for localized chemo-thermal tumor therapy. Advanced Science 2018, 1700782.

(7)Wang DH, Peng F, Li JH, Qiao YQ, Li QW, Liu XY*. Butyrate inserted Ni-Ti layered double hydroxide film for H2O2 mediated tumor and bacteria killing. Materials Today, 2017, 20(5), 238-257.

(8)Li BE, Zhang L, Wang DH*, Liu XY*, Li HP, Zhou LX, Liang CY, Zhao XY. Thermo-sensitive hydrogel on anodized titanium surface to regulate immune response, Surface & Coating Technology,2021,405.

(9)Li BE, Ma JW, Wang DH*, Liu XY*, Li, HP; Zhou, LX; Liang, CY; Wang, HS. Self-adjusting antibacterial properties of Ag-incorporated nanotubes on micro-nanostructured Ti surfaces [J]. Biomaterials Science, 2019, DOI:10.1039/c9bm00862d.

(10) Wang DH, Ge NJ, Li JH, Qiao YQ, Zhu HQ, Liu XY*. Selective tumor cell inhibition effect of Ni-Ti layered double hydroxides thin films driven by the reversed pH gradients of tumor cells. ACS Applied Materials & Interfaces, 2015, 7(15): 7843-7854.